Lousy/Intensive Metabolizers, CYP2D6 The formation with the Lively metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. About 7% with the populace has diminished action of the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme procedure. These men and women are “weak metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, among the https://janed319ekp3.vigilwiki.com/user