Pore formation is the most energy-demanding step during virus-induced membrane fusion. where high curvature of the fusion pore rim increases the spacing between lipid headgroups. exposing the hydrophobic interior of the membrane to water. How protein fusogens breach this thermodynamic barrier to pore formation is unclear. https://www.bekindtopets.com/hot-offer-Stuart-Product-Emcelle-Tocopherol-Vitamin-E-Liquid-1-Liter-hot-value/