There is a release of norepinephrine within the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors during the dorsal horn to reduce afferent discomfort transmission and deliver analgesia. Therefore, medicine like clonidine that goal alpha-two receptors can influence the transmission of soreness. Clonidine is distributed in breast milk; caution https://raymondo670qkc3.wikisona.com/user