Listed here, we display that conolidine, a pure analgesic alkaloid used in classic Chinese medication, targets ACKR3, thereby offering extra evidence of a correlation concerning ACKR3 and ache modulation and opening choice therapeutic avenues for the therapy of Continual discomfort. Conolidine belongs to a larger class of natural products, https://kirkv937vaa6.thebindingwiki.com/user